But the Air Force's Global Hawk has never flown a mission over the United States.
That is set to change Monday, when the first Global Hawk is scheduled to land at Beale Air Force Base in northern California.
"This landmark flight has historic implications since it's the first time a Global Hawk has not only flown from Beale, but anywhere in the United States on an official Air Combat Command mission," base spokesman Capt. Michael Andrews said in a statement.
Beale is to have seven Global Hawks by 2009. It is currently the only U.S. base with the drones. Eventually the Air Force's fleet will include 54 of the Global Hawks, but most will be based overseas.