An old debunker's adage goes (in various iterations), "You can never be too skeptical." Lately, largely because of my run-ins with "skeptics" of evolution, I've become increasingly convinced that this slogan is fundamentally flawed. Consider, for example, what happens when a predisposition towards skepticism leads one to doubt a consensus view in the scientific community, or to pooh-pooh a possibility that many leading scientists consider highly likely. Taken to extremes, it can lose its usefulness and even lead to perverse outcomes.
Abuses of Skepticism