"If you're good, if you're any good at all, you put yourself in a situation where reality could come around and -- WHACK! -- knock you down. That's what you really are afraid of. If you don't have that, you're not playing science,"

"That lab was a strange, strange place. A lot of weird, weird, different kinds of people. The dean would look at it and say, 'That's a strange damn place.' I'd answer: 'Have you looked at me?' "

Much of the work was some variation of two basic LTP experiments. One involved isolating single neurons, which, using high-powered microscopes, were identified, then pinched with a clamp to hold them in place. This was exceptionally tedious. Researchers could go entire days without successfully clamping a single cell.

"There is so damned much housekeeping. The problem is, biology is a very horizontal science. You have this result over here, that one over there. None of it lines up."

One man's epic quest for understanding